ISBN: 9780262356145 | 448 pp. | September 2019

The Neocortex


Over the past decade, technological advances have dramatically increased information on the structural and functional organization of the brain, especially the cerebral cortex. This explosion of data has radically expanded our ability to characterize neural circuits and intervene at increasingly higher resolutions, but it is unclear how this has informed our understanding of underlying mechanisms and processes.

In search of a conceptual framework to guide future research, leading researchers address in this volume the evolution and ontogenetic development of cortical structures, the cortical connectome, and functional properties of neuronal circuits and populations. They explore what constitutes “uniquely human” mental capacities and whether neural solutions and computations can be shared across species or repurposed for potentially uniquely human capacities.

Danielle S. Bassett, Randy M. Bruno, Elizabeth A. Buffalo, Michael E. Coulter, Hermann Cuntz, Stanislas Dehaene, James J. DiCarlo, Pascal Fries, Karl J. Friston, Asif A. Ghazanfar, Anne-Lise Giraud, Joshua I. Gold, Scott T. Grafton, Jennifer M. Groh, Elizabeth A. Grove, Saskia Haegens, Kenneth D. Harris, Kristen M. Harris, Nicholas G. Hatsopoulos, Tarik F. Haydar, Takao K. Hensch, Wieland B. Huttner, Matthias Kaschube, Gilles Laurent, David A. Leopold, Johannes Leugering, Belen Lorente-Galdos, Jason N. MacLean, David A. McCormick, Lucia Melloni, Anish Mitra, Zoltán Molnár, Sydney K. Muchnik, Pascal Nieters, Marcel Oberlaender, Bijan Pesaran, Christopher I. Petkov, Gordon Pipa, David Poeppel, Marcus E. Raichle, Pasko Rakic, John H. Reynolds, Ryan V. Raut, John L. Rubenstein, Andrew B. Schwartz, Terrence J. Sejnowski, Nenad Sestan, Debra L. Silver, Wolf Singer, Peter L. Strick, Michael P. Stryker, Mriganka Sur, Mary Elizabeth Sutherland, Maria Antonietta Tosches, William A. Tyler, Martin Vinck, Christopher A. Walsh, Perry Zurn

Table of Contents

  1. Preface
  2. List of Contributors
  3. 1. Introduction
  4. 2. Cortical Specification and Neuronal Migration
  5. 3. The Evolution of the Human Cerebral Cortex Development: A Genomic Perspective
  6. 4. What Happens When It Goes Wrong?: Using Human Genetics to Understand Human Brain Development and Evolution
  7. 5. Evolution and Ontogenetic Development of Cortical Structures
  8. 6. Brain Networks: How Many Types Are There?
  9. 7. Network Models in Neuroscience
  10. 8. Neuronal Morphology and Its Significance
  11. 9. Functional Architecture of the Cerebral Cortex
  12. 10. Cortical Dynamics
  13. 11. Computational Elements of Circuits
  14. 12. Coding in Large-Scale Cortical Populations
  15. 13. Functional Properties of Circuits, Cellular Populations, and Areas
  16. 14. Complexity and Computation in the Brain: The Knowns and the Known Unknowns
  17. 15. Human Singularity and Symbolic Tree Structures: The Demodularization Hypothesis
  18. 16. Phylogeny and Ontogeny in Human Neuroscience
  19. 17. Computation and Its Neural Implementation in Human Cognition
  20. Bibliography
  21. Subject Index
  22. Strüngmann Forum Report Series