ISBN: 9780262083461 | 1016 pp. | April 2006

Table of Contents
  Foreword
  Preface to the Second Edition
  Preface to the First Edition
I. HISTORY AND BACKGROUND TO MODERN TESTING
  1. History of the Electroretinogram
A. F. de Rouck
  2. History of Electro-Oculography
Geoffrey B. Arden
  3. History of Visual Evoked Cortical Testing
Graham F. A. Harding
II. ANATOMY OF THE RETINA, PRINCIPLES OF CELL BIOLOGY IN THE VISUAL PATHWAYS: FUNCTIONAL, PHYSIOLOGICAL, BIOCHEMICAL, MOLECULAR, BIOLOGICAL
  4. The Photoreceptor–Retinal Pigment Epithelium Interface
Gregory S. Hageman and Lincoln V. Johnson
  5. Membrane Mechanisms of the Retinal Pigment Epithelium
Olaf Strauss
  6. Functional Organization of the Retina
Helga Kolb
  7. Phototransduction and Photoreceptor Physiology
W. Clay Smith
  8. Synaptic Transmission: Sensitivity Control Mechanisms
Gertrude Falk and Richard Shiells
  9. Structure and Function of Retinal Synapses: Role of Cell Adhesion Molecules and Extracellular Matrix
William J. Brunken, Thomas Claudepierre, Mary K. Manglapus, and Dale D. Hunter
  10. Central Disorders of Vision in Humans
Christopher A. Girkin
III. ORIGINS OF SLOW ELECTROPHYSIOLOGICAL COMPONENTS
  11. Origin and Significance of the Electro-Oculogram
Geoffrey B. Arden
  12. Orgins of the Electroretinogram
Laura J. Frishman
  13. The Origin of the Pattern Electroretinogram
Michael Bach and Michael B. Hoffmann
  14. The Multifocal Electroretinographic and Visual Evoked Potential Techniques
Donald C. Hood
  15. Origin of the Visual Evoked Potentials
Manfred Fahle and Michael Bach
IV. EQUIPMENT
  16. Data Acquisition Systems for Electrodiagnostic Testing
Chris Hogg and Steven Nusinowitz
  17. Electrodes for Visual Testing
Stuart G. Coupland
  18. Amplifiers and Special-Purpose Data Acquisition Systems
J. Vernon Odom
  19. Stimulus Devices, Calibration, and Measurement of Light
Chris Hogg
V. DATA ACQUISITION
  20.1. Introduction to the ISCEV Standards
Michael F. Marmor and Eberhart Zrenner (for the international society for clinical electrophysiology of vision)
  20.2. EOG Standard
Michael F. Marmor and Eberhart Zrenner (for the international society for clinical electrophysiology of vision)
  20.3. Standard for Clinical Electroretinography
Michael F. Marmor, Graham E. Holder, Mathias W. Seeliger, and Shuichi Yamamoto (for the international society for clinical electrophysiology of vision)
  20.4. Standard for Pattern Electroretinography
Michael Bach, Marko Hawlina, Graham E. Holder, Michael F. Marmor, Thomas Meigen, Vaegan, and Yozo Miyake (for the international society for clinical electrophysiology of vision)
  20.5. Visual Evoked Potentials Standard
J. Vernon Odom, Michael Bach, Colin Barber, Mitchell Brigell, Michael F. Marmor, Alma Patrizia Tormene, Graham E. Holder, and Vaegan (for the international society for clinical electrophysiology of vision)
  20.6. Guidelines for Basic Multifocal Electroretinography
Michael F. Marmor, Donald C. Hood, David Keating, Mineo Kondo, Mathias W. Seeliger, and Yozo Miyake (for the international society for clinical electrophysiology of vision)
  21. Multifocal Techniques
David Keating and Stuart Parks
  22. The Pattern Electroretinogram
Graham E. Holder
  23. Assessing Infant Acuity, Fusion, and Stereopsis with Visual Evoked Potentials
Eileen E. Birch
  24. Aging and Pattern Visual Evoked Cortical Potential
Emiko Adachi-Usami
  25. Aberrant Albino and Achiasmat Visual Pathways: Noninvasive Electrophysiological Assessment
P. Apkarian and L. J. Bour
  26. Clinical Psychophysical Techniques
Kenneth R. Alexander
  27. Measurement of Contrast Sensitivity
Geoffrey B. Arden
  28. Suppressive Rod-Cone Interaction
Thomas E. Frumkes
  29. The Use of Fluorescein Angiography as an Adjunct to Electrophysiological Testing
John R. Heckenlively
VI. DATA ANALYSIS
  30. Experimental Design and Data Analyses in Vision Function Testing
Steven Nusinowitz
  31. Analytical Techniques
L. Henk van der Tweel and Oscar Estévez
  32. Reverse Correlation Methods
Bevil R. Conway and Margaret S. Livingstone
  33. Stimulus-Response Functions for the Scotopic b-Wave
Anne B. Fulton and Ronald. M. Hansen
  34. Kernel Analysis
J. Vernon Odom
  35. Measuring the Health of the Human Photoreceptors with the Leading Edge of the a-Wave
Donald C. Hood and David G. Birch
VII. PRINCIPLES OF CLINICAL TESTING
  36. Localizing Lesions in the Visual System
Graham E. Holder
  37. Paired-Flash ERG Analysis of Rod Phototransduction and Adaptation
David R. Pepperberg
  38. Hyperabnormal (Supranormal) Electroretinographic Responses
John R. Heckenlively and Steven Nusinowitz
  39. Technical Issues in Evaluating Patients for Therapeutic Trials
Beth Edmunds, Peter J. Francis, and Richard G. Weleber
VIII. OTHER PROTOCOLS FOR RECORDING OF ERG AND SLOWER POTENTIALS, TECHNICAL ISSUES, AND AUXILIARY TESTING TECHNIQUES
  40. Early Receptor Potential
Gordon L. Fain
  41. Nonphotic Standing Potential Responses: Hyperosmolarity, Bicarbonate, and Diamox Responses
Kazuo Kawasaki, Jhoji Tanabe, and Kenji Wakabayashi
  42. Direct Current Electroretinogram
Sven Erik G. Nilsson
  43. The Oscillatory Potentials of the Electroretinogram
Pierre LaChapelle
  44. Flicker Electroretinography
David G. Birch
  45. Chromatic Recordings of Electroretinograms
Kazuo Kawasaki, Jhoji Tanabe, Kenji Wakabayashi, and Yutaka Shirao
  46. Adaptation Effects on the Electroretinogram
Peter Gouras and Cynthia Mackay
  47. Clinical Electrophysiological and Psychophysical Investigations into Color Defects
Geoffrey B. Arden and Thomas Berninger
  48. Causes and Cures of Artifacts
Geoffrey B. Arden
IX. PRINCIPLES OF CLINICAL TESTING AND EVALUATION OF VISUAL DYSFUNCTION FROM DEVELOPMENTAL, TOXIC, AND ACQUIRED CAUSES
  49. Testing Levels of the Visual System
John R. Heckenlively, Richard G. Weleber, and Geoffrey B. Arden
  50. Effects of High Myopia on the Electroretinogram
Steven Nusinowitz
  51. Electrodiagnostic Testing in Malingering and Hysteria
Graham E. Holder
  52. Developmental Amblyopia
Dorothy Thompson
  53. Visual Evoked Potentials in Cortical Blindness
Emiko Adachi-Usami
  54. Drug Side Effects and Toxicology of the Visual System
Eberhardt Zrenner
  55. Mitochondrial Diseases
Alvin B. H. Seah and Nancy J. Newman
X. EVALUATION OF VASCULAR DISEASES, INFLAMMATORY STATES, AND TUMORS
  56. Diseases of the Middle Retina: Venous and Arterial Occlusions
Mary A. Johnson
  57. Acute Disorders of the Outer Retina, Pigment Epithelium and Choroid
Scott E. Brodie
  58. Autoimmune Retinopathy, CAR and MAR Syndromes
John R. Heckenlively, Natalia Aptsiauri, and Graham E. Holder
  59. Ischemic Optic Neuropathy
Graham E. Holder
XI. CLINICAL DESCRIPTIONS: RETINAL PIGMENT EPITHELIUM DISEASES
  60. Gyrate Atrophy of the Choroid and Retina
Richard G. Weleber
  61. Dominant Drusen
Elise Héon, Francis Munier, and Colin Willoughby
  62. Stargardt Disease
David G. Birch
  63. Bietti's Crystalline Dystrophy of the Cornea and Retina
Richard G. Weleber and David J. Wilson
  64. Leber Congenital Amaurosis
Robert K. Koenekoop
  65. Pattern Dystrophies
Michael F. Marmor
  66. Best Vitelliform Macular Dystrophy
Gerald A. Fishman
  67. Sorsby's Fundus Dystrophy
Michael P. Clarke and Keith W. Mitchell
XII. DISEASES OF THE OUTER RETINA
  68. Choroideremia
Ian M. MacDonald and Miguel C. Seabra
  69. Retinitis Pigmentosa
David G. Birch
  70. Cone Dystrophies and Degenerations
John R. Heckenlively
  71. Vitamin A Deficiency
Ronald E. Carr
XIII. DISEASES OF THE MIDRETINA (INCLUDING NEGATIVE WAVEFORM DISEASES)
  72. Differential Diagnosis of the Electronegative Electroretinogram
Richard G. Weleber and Peter J. Francis
  73. Juvenile X-Linked Retinoschisis
Paul A. Sieving, Ian M. MacDonald, and Naheed W. Khan
  74. Congenital Stationary Night Blindness
Yozo Miyake
  75. Quinine Retinopathy
Graham E. Holder
XIV. OPTIC NERVE AND CENTRAL NERVOUS SYSTEM DYSFUNCTION
  76. Leber's Hereditary Optic Neuropathy
Yoshihisa Oguchi
  77. The Pattern Electroretinogram in Glaucoma and Ocular Hypertension
Gary L. Trick
  78. Chiasmal and Retrochiasmal Lesions
Graham E. Holder
  79. Optic Nerve and Central Nervous Dysfunctions: Parkinson's Disease and Multiple Sclerosis
Ivan Bodis-Wollner and Andrea Antal
  80. Diseases of Fatty Acid Storage and Metabolism: Neuronal Ceroid Lipofuscinoses and the Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
David G. Birch and Richard G. Weleber
XV. ANIMAL TESTING
  81. Evaluating Retinal Function in the Mouse Retina with the Electroretinogram
Steven Nusinowitz and John R. Heckenlively
  82. Electroretinograms of Dog and Chicken
Simon Petersen-Jones, Nalinee Tuntivanich, Fabiano Montiani-Ferreira, and Naheed W. Khan
  83. Electroretinographic Testing in Larger Animals
Kristina Narfström
  84. Visual Evoked Potentials in Animals
William Ridder
  Contributors
  Index

 

Principles and Practice of Clinical Electrophysiology of Vision, 2nd Edition

Overview

This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science.

The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.