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Journal of Cognitive Neuroscience

June 2007, Vol. 19, No. 6, Pages 1004-1012.
(doi: 10.1162/jocn.2007.19.6.1004)
© 2007 Massachusetts Institute of Technology
Functional Interactions during the Retrieval of Conceptual Action Knowledge: An fMRI Study
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Impaired retrieval of conceptual knowledge for actions has been associated with lesions of left premotor, left parietal, and left middle temporal areas [Tranel, D., Kemmerer, D., Adolphs, R., Damasio, H., & Damasio, A. R. Neural correlates of conceptual knowledge for actions. Cognitive Neuropsychology, 409–432, 2003]. Here we aimed at characterizing the differential contribution of these areas to the retrieval of conceptual knowledge about actions. During functional magnetic resonance imaging (fMRI), different categories of pictograms (whole-body actions, manipulable and nonmanipulable objects) were presented to healthy subjects. fMRI data were analyzed using SPM2. A conjunction analysis of the neural activations elicited by all pictograms revealed ( p