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Category-Specific Impairments in Dementia of the Alzheimer-Type

 Frances Duffy and Joanna Beaton
  
 

Abstract:
here is considerable evidence to suggest that semantic memory is impaired early in the course of dementia of the Alzheimer-type (DAT). The present study compared semantic memory in DAT patients and healthy elderly control subjects. Four tests were employed which involved mechanisms of either voluntary or automatic access to information in semantic memory. Both on- and off-line tasks were chosen to investigate whether reported deficits in semantic memory in DAT result from a loss of stored information or simply from a failure to access stored information. The tasks assessing voluntary access included category fluency, within category word-picture matching, and visual confrontation naming. The test of automatic access was naming latency on a semantic priming test. Test stimuli comprised category co-ordinates from both living and non-living categories. The results showed that although DAT patients generated fewer exemplars on the category fluency test compared to control subjects, no category specific impairment was found. On the word-picture matching task, DAT patients made few errors, whereas, on picture naming, they made significantly more errors on living items compared to non-living items. In contrast, however, DAT patients only showed priming effects for living prime-target pairs. The results are discussed in terms of the information loss versus access failure hypotheses.

 
 


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