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Abstract:
The serial reaction time task was used to investigate
sequence learning in patients with frontal-lobe lesions and
patients with cerebellar atrophy. Frontal-lobe patients produced
abnormal accuracy rates, but evidenced sequence learning with the
reaction-time measure. In contrast, cerebellar-atrophy patients
produced normal accuracy rates while showing no change in reaction
times. These findings reveal a double dissociation between the
performance of frontal-lobe patients and cerebellar-atrophy
patients. Although sometimes interacting, the cerebellum and the
prefrontal cortex appear to be able to play independent roles in
complex sequence learning.
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