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Processing Sentences and Discourse in Patients with Alzheimer's Disease.

 Amit Almor, Maryellen MacDonald, Daniel Kempler, Elaine Andersen and Lorraine Tyler
  
 

Abstract:
We report results from two cross-modal naming experiments designed to examine the processing of number agreement in sentences and in discourse by patients with Alzheimer's disease and age-matched normal controls. Experiment 1 tested the processing of subject-verb number agreement within sentences and Experiment 2 investigated the processing of pronoun-antecedent number agreement across sentences. Both experiments included a length manipulation such that processing was tested with varying amounts of intervening material between the agreeing constituents. Verbal working memory was assessed for all participants.The results of these two experiments revealed a 3-way dissociation between processing number agreement in sentences and in discourse: 1. Intervening material only hindered agreement processing in sentences (Experiment 1) but not in discourse (Experiment 2). 2. The Alzheimer's patients were only impaired in discourse processing (Experiment 2) but not in sentence processing (Experiment 1). 3. Working memory performance correlated with discourse processing performance (Experiment 2) but not with sentence processing performance (Experiment 1). These results are not only compatible with a modular view of separate processors for sentences and for discourse but are also compatible with an integrated view whereby difference in processing do not implicate different processors but merely reflect the different properties of the input. We present a Bayesian model which, based on a single mechanism, explains our findings in terms of differences in the frequency of the dependencies we tested, and the predictability of the dependent constituent given the other constituent.

 
 


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