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Brain Plasticity and Rehabilitation of Motor Functions

 Emilio Bizzi
  
 

Abstract:
(Invited Talks)

Recently, great strides have been made in understanding the neural foundations of motor behavior. Through the combined efforts of biologists, computer scientists, physicists, and engineers, a picture has begun to emerge of the way in which the nervous system regulates movement. The goal of my presentation is to explain what neuroscience has established so far about how the central nervous system (CNS) deals with the complex dynamics of our limbs as they interact with a variable and often unpredictable environment. I will review how scientists have approached the study of movement, the problems they have encountered, and the solutions they have proposed. Specifically, I will focus 1) on the ways in which the CNS may produce the forces necessary to generate movements, and 2) on the issue of motor learning. I will show how motor memories may be represented, stored, and retrieved through the formation of internal models of limb dynamics. 3) I will discuss the utilization of this knowledge for motor rehabilitation in patients affected by stroke and brain injury.

Professor Emilio Bizzi is the Eugene McDermott Professor in the Brain Sciences and Human Behavior. His research is directed toward the understanding of movement control in biological systems and the neural substrate for motor learning. Dr. Bizzi obtain his M.D. from the University of Rome, and came to MIT in 1969. Dr. Bizzi has been the Director of Whitaker College of Health Sciences, Technology, and Management (1983-89) and Head of the Department of Brain and Cognitive Sciences (1986-97). He is a member of the National Academy of Sciences (1986) and the American Academy of Sciences (1980).

 
 


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