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First Steps toward a Theory of Mental Force: PET Imaging of Systematic Cerebral Changes after Psychological Treatment of Obsessive-Compulsive Disorder

 Jeffrey M. Schwartz
  
 

Abstract:
Obsessive-compulsive disorder (OCD) is a common neuropsychiatric condition, affecting approximately 2 percent of the general population (Jenike et al. 1998). It is characterized by bothersome intrusive thoughts and urges that frequently lead to dysfunctional repetitive behaviors such as excessive hand washing or ritualistic counting and checking. As the result of a concerted research effort over the past two decades there has emerged a growing consensus that brain circuitry contained within the orbital frontal cortex, anterior cingulate gyrus and the basal ganglia is intimately involved in the expression of the symptoms of OCD (for recent reviews see Schwartz 1997a and b, Jenike et al. 1998).

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