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Differential Memory Encoding of Fused and Associated Concepts Revealed by Spatiotemporal Brain Imaging

 John Kounios, Roderick W. Smith, Wei Yang and Peter Bachman
  
 

Abstract:
Abstract: We employed source-localization of dense-array ERP recordings co-registered to structural MRI to test the hypothesis that the encoding into memory of associated and fused pairs of concepts relies on different brain areas. This was done using a conceptual combination paradigm in which subjects' task was to try to fuse a sequentially presented pair of words into a single concept (e.g., as in a compound noun). Success or failure of fusion for each pair was indicated by button-press. This was followed by a memory test for temporal order of pair items in which half of the test pairs were in the reverse order compared to the encoding phase. The subsequent memory encoding effect for fused and non-fused (i.e., associated) pairs in the encoding phase was computed by performing a median split on the reaction times at test, and by averaging encoding phase ERPs according to fast and slow test-phase responses. Source localization of this later-fast minus later-slow encoding effect for fused and associated pairs was performed using a realistic head model derived from structural MRI.

 
 


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