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Abstract:
Abstract: The anterior cingulate is believed to play a
crucial role in the regulation of thought and action. Recent
evidence suggests that the anterior cingulate may play a role in
the detection of inappropriate responses. We employed event-related
functional magnetic resonance imaging techniques to examine the
neural responses to appropriate (correct rejects and correct hits)
and inappropriate (errors of commission) behavioral responses
during a Go/No Go task. Analyses of the inappropriate responses
revealed extensive activation in the rostral anterior cingulate
cortex and in the left lateral frontal cortex. These areas were not
activated for correctly classified trials (e.g., correct rejects
and correct hits). These data suggest that the rostral anterior
cingulate and left lateral frontal cortex are integral components
of the brain's error checking system.
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