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Perceptual and Conceptual Implicit Memory in Multiple Sclerosis Patients

 Diana Portnoy, Andrew Yonelinas, Donald Goodkin and Tracy Luks
  
 

Abstract:
Abstract: Previous studies examining implicit memory in Multiple Sclerosis (MS) patients report that the patients exhibit relatively intact implicit memory as measured in visual word stem completion tasks. Those studies, however, did not control for the use of intentional retrieval, and the MS patients were not separated into specific disease type subgroups. Recent studies with subgroups indicate that Primary Progressive MS patients (PP) may exhibit a clinical phenotype of MS distinct from those of patients in the more common Relapsing Remitting (RR) and Secondary Progressive (SP) subgroups. The current study investigated both perceptual and conceptual implicit memory using word fragment completion and exemplar generation tasks. Furthermore, the contribution of explicit memory to the implicit tests was assessed, and explicit memory was measured using a free recall procedure. Preliminary results indicate that explicit memory is disrupted in MS patients, but that conceptual implicit memory is relatively preserved. Moreover, only the PP subgroup appears to exhibit a deficit in perceptual implicit priming.

 
 


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