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Perceptual False Recognition in Alzheimer's Disease: Impairment of Gist-based Memory

 Andrew E. Budson, Rahul Desikan, Kirk R. Daffner and Daniel L. Schacter
  
 

Abstract:
Abstract: Previous research has found that patients with probable Alzheimer's disease (AD) show lower levels of false recognition of semantic associates than do healthy elderly adults. To investigate whether this finding is attributable to semantic impairments in AD patients, the authors examined false recognition of perceptually related novel objects with little semantic content in AD patients and elderly adults. Using corrected recognition scores to control for unrelated false alarms, it was found that AD patients showed lower levels of both true and false recognition of novel objects than did elderly adults. These results suggest that the previous difference in false recognition of semantic associates observed between AD patients and elderly adults is not entirely attributable to AD patients' semantic memory deficits, but also involves poorly developed gist information of the AD patients.

 
 


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