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False Recognition in Alzheimer's Disease: Inability to Use the Distinctiveness Heuristic

 Joanne Sitarski, Andrew E. Budson, Kirk R. Daffner and Daniel L. Schacter
  
 

Abstract:
Abstract: Patients with Alzheimer's disease (AD) suffer from distortions of memory that may impair their ability to live independently. False recognition is a type of memory distortion in which one mistakenly claims to have previously encountered a novel item that is related to a studied item. We have previously shown that healthy elderly adults--but not AD patients--can suppress their false recognition of semantic associates across multiple study-test trials. Previous work in our laboratory has shown that false recognition in elderly adults can be greatly suppressed if subjects study pictorial representations of each study item presented by auditory modality. Schacter et al. (1999) hypothesized that this suppression occurs because pictorial encoding enables elderly subjects to employ a distinctiveness heuristic, whereby subjects have access to distinctive details about a studied item and are more likely to reject related lures that do not support their detailed recollections. The goal of our research was to investigate whether AD patients could also employ such a heuristic to suppress their false recognition. Preliminary results suggest that while elderly adults are able to use a distinctiveness heuristic to reduce their level of false recognition, AD patients can not.

 
 


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