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An Event-related Functional Magnetic Resonance Imaging (fmri) Investigation of Stimulus-response Compatibitiy

 Edward L. Maclin, Monica Fabiani, Randy Buckner and Gabriele Gratton
  
 

Abstract:
Stimulus-response compatibility is expected to introduce an increased load in working memory and influence response preparation and execution. We examined the brain regions involved in these sets of processes by using an event-related fMRI approach. Stimuli were arrows presented to the left and right of fixation and pointing either to the left or to the right. Subjects had to respond on the basis of the direction of the arrow and to ignore their location. This created conditions in which the location and direction of the arrow conflicted. Functional MRI data were recorded using a 1.5 T Siemens-Vision system equipped for echoplanar imaging. Preliminary analysis of the results indicated event-related BOLD responses in (a) medial occipital cortex contralateral to the hemifield of stimulation; (b) pre-central cortex contralateral to the responding hand; (c) pre-SMA in the conflict with respect to the no-conflict conditions. In addition, the contralateral pre-central response appeared larger in the no-conflict conditions. These data indicate that several areas may be activated in conflict conditions.

 
 


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