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Memory Retrieval of Cognitive Associations Revealed by Spatiotemporal Brain Imaging

 J. Kounios, R. W. Smith, W. Yang, P. Bachman and M. D'Esposito
  
 

Abstract:
We employed LORETA source imaging of dense-array ERP recordings co-registered to structural MRI to test the hypothesis that the retrieval from memory of associated and fused pairs of concepts relies on different brain areas. This was done by examining associative recognition following a conceptual-combination encoding task in which subjects task was to try to fuse a sequentially presented pair of words into a single concept (e.g., as in a compound noun). Success or failure of fusion for each pair was indicated by button-press. The memory test was for temporal order of pair items in a which half of the test pairs were in the reverse order compared to the encoding phase. The difference between same- and reverse-order pairs was localized separately for fused and juxtaposed pairs. Results show different patterns of reaction times, ERP topographies, and localized brain sources for the same/reverse-order effect for retrieval of fused and juxtaposed pairs.

 
 


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