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Abstract:
Our goal was to study structural-psychological relationships
independent of age. In this paper, magnetic resonance imaging (MRI)
was used to derive measurements of volume of left and right
hippocampal (HP) formations, prefrontal gray, white matter and
subarachnoid cerebrospinal fluid (PS), and the subarachnoid
cerebrospinal fluid of the left (LV) and right ventricles (RV).
Tests of primary memory (digit span, visual matrices) and tests of
secondary memory with immediate and delayed recall components
(paragraph, paired associate, list recall, facial recognition) were
also applied. Wisconsin Card Sorting Test was also evaluated. WAIS
test was used as a control measure for intelligence. Normal
subjects between 24 and 67 years old were studied. All subjects had
a normal IQ, and all were universitary graduated people. For the
MRI, 124 slides of 1.5 mm were obtained with a GE of 1.5 T.
Significant positive correlations with age were found for PS , LV,
RV and verbal IQ, and negative with primary memory, immediate and
delayed recall. Highly significant negative correlations,
independent of age, were found between RV, LV and correct responses
in the Wisconsin test. HP volumes had a negative correlation with
correct delayed responses. These results supported the differential
mnemonic role of prefrontal and HP structures.
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