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Abstract:
Functional magnetic resonance imaging (fMRI) was used to
investigate low frequency temporal correlations in blood
oxygenation level between Broca's area and Wernicke's area. These
brain regions, which have long been implicated in language
processing, are nonadjacent, nonhomologous, and known to be
strongly neurally connected. The signals from Broca's area and
Wernicke's area were found to be correlated during resting state
scans and this correlation was found to increase when subjects
listened to continuous speech. These findings are consistent with
the hypothesis that low-frequency resting state correlations in
BOLD (Blood Oxygenation Level Dependent) signals can reveal
functional connections in high-level cognitive systems. In
addition, they support the possibility that the degrees of
interactions between brain regions are reflected by the magnitudes
of such correlations.
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