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Abstract:
In 1903 Arnold Pick used the term "reduplicative paramnesia"
(RP) to describe a specific and limited disturbance of memory
characterized by a subjective certainty that a familiar place or
person has been duplicated. RP has been associated with
post-traumatic brain injury, strokes, tumors, dementias, and
psychiatric conditions. Although several investigators, including
Pick, have hypothesized that RP is a disconnection syndrome
disrupting memory,In 1903 Arnold Pick use d the term "reduplicative
paramnesia" (RP) to describe a specific and limited disturbance of
memory characterized by a subjective certainty that a familiar
place or person has been duplicated. RP has been associated with
post-traumatic brain injury, strokes, tumors, dementias, and
psychiatric conditions. Although several investigators, including
Pick, have hypothesized that RP is a disconnection syndrome
disrupting memory, the conclusions of previous reports have been
weakened by the fact that there is often diffuse, multifocal, or
cortical injury. We present a case report of a 45 year old
left-handed alcoholic man with a single, small, linear white-matter
stroke in the left temporo-parieto-occipital junction who developed
acute onset of subtle RP for place. Neuropsychological testing
revealed mild difficulties with tests of complex attention and
severe deficits in non-verbal memory and visuospatial processing.
This case provides anatomical and neuropsychological support for
the theory that RP is a syndrome which may develop in a vulnerable
brain by a white-matter disconnection between the non-dominant
hippocampus and the visual cortex. the conclusions of previous
reports have been weakened by the fact that there is often diffuse,
multifocal, or cortical injury. We present a case report of a 45
year old left-handed alcoholic man with a single, small, linear
white-matter stroke in the left temporo-parieto-occipital junction
who developed acute onset of subtle RP for place.
Neuropsychological testing revealed mild difficulties with tests of
complex attention and severe deficits in non-verbal memory and
visuospatial processing. This case provides anatomical and
neuropsychological support for the theory that RP is a syndrome
which may develop in a vulnerable brain by a white-matter
disconnection between the non-dominant hippocampus and the visual
cortex.
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