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In 1949, Sorsby and Mason described five families with a dominantly inherited central retinal dystrophy leading to visual loss in the fifth decade.34 Visual loss occurred either because of subretinal neovascular membranes leading to disciform scarring or because of chorioretinal atrophy at the macula. There was gradual progression of the condition to involve the retinal periphery, such that ambulatory vision was lost up to 35 years later.34 The condition has become known as Sorsby's fundus dystrophy (SFD). For general and electrophysiological reviews, see Berninger,5 Iannaccone,22 and Scullica and Falsini.32
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